BDBM50058479 2,6-Dimethyl-4-[4-(4-{2-methyl-1-[(R)-3-(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-2-aza-bicyclo[2.2.2]octane-2-carbonyl]-propylcarbamoyl}-benzenesulfonylaminocarbonyl)-phenyl]-pyridine-3,5-dicarboxylic acid diethyl ester::CHEMBL435348

SMILES CCOC(=O)c1c(C)nc(C)c(C(=O)OCC)c1-c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(cc1)C(=O)N[C@@H](C(C)C)C(=O)N1C2CCC(CC2)[C@@H]1C(=O)NC(C(C)C)C(=O)C(F)(F)F

InChI Key InChIKey=OHCTULZDELJOOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058479   

TargetNeutrophil elastase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50058479(2,6-Dimethyl-4-[4-(4-{2-methyl-1-[(R)-3-(3,3,3-tri...)
Affinity DataIC50: 41nMAssay Description:Inhibitory concentration against Human Leukocyte Elastase from human sputumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed