BDBM50058417 5-{4-chloro-3-[(1E)-3-methyltriaz-1-enyl]phenyl}-6-ethylpyrimidine-2,4-diamine::CHEMBL53902

SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)c(NN=NC)c1

InChI Key InChIKey=BFJDBUGRSFNCKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058417   

TargetDihydrofolate reductase(Pneumocystis carinii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058417(5-{4-chloro-3-[(1E)-3-methyltriaz-1-enyl]phenyl}-6...)
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro inhibitory concentration against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058417(5-{4-chloro-3-[(1E)-3-methyltriaz-1-enyl]phenyl}-6...)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed