BDBM50058399 5-[4-Chloro-3-(morpholin-4-ylazo)-phenyl]-6-ethyl-pyrimidine-2,4-diamine::CHEMBL293265::CHEMBL48203

SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)c(c1)\N=N\N1CCOCC1

InChI Key InChIKey=DIWISMVJGBGRMV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50058399   

TargetDihydrofolate reductase(Pneumocystis carinii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058399(CHEMBL48203 | CHEMBL293265 | 5-[4-Chloro-3-(morpho...)
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibitory concentration against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058399(CHEMBL48203 | CHEMBL293265 | 5-[4-Chloro-3-(morpho...)
Affinity DataIC50: 4.70E+3nMAssay Description:In vitro inhibitory concentration against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058399(CHEMBL48203 | CHEMBL293265 | 5-[4-Chloro-3-(morpho...)
Affinity DataIC50: 2.63E+4nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058399(CHEMBL48203 | CHEMBL293265 | 5-[4-Chloro-3-(morpho...)
Affinity DataIC50: 190nMAssay Description:Inhibitory concentration against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058399(CHEMBL48203 | CHEMBL293265 | 5-[4-Chloro-3-(morpho...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50058399(CHEMBL48203 | CHEMBL293265 | 5-[4-Chloro-3-(morpho...)
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058399(CHEMBL48203 | CHEMBL293265 | 5-[4-Chloro-3-(morpho...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed