BDBM50058396 5-{4-chloro-3-[(1E)-3-methyl-3-propyltriaz-1-enyl]phenyl}-6-ethylpyrimidine-2,4-diamine::CHEMBL293822::CHEMBL294468

SMILES CCCN(C)\N=N\c1cc(ccc1Cl)-c1c(N)nc(N)nc1CC

InChI Key InChIKey=RRWJNQNCAHFPKE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50058396   

TargetDihydrofolate reductase(Pneumocystis carinii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058396(CHEMBL294468 | CHEMBL293822 | 5-{4-chloro-3-[(1E)-...)
Affinity DataIC50: 7.60E+3nMAssay Description:In vitro inhibitory concentration against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058396(CHEMBL294468 | CHEMBL293822 | 5-{4-chloro-3-[(1E)-...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058396(CHEMBL294468 | CHEMBL293822 | 5-{4-chloro-3-[(1E)-...)
Affinity DataIC50: 1.02E+4nMAssay Description:In vitro inhibitory concentration against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50058396(CHEMBL294468 | CHEMBL293822 | 5-{4-chloro-3-[(1E)-...)
Affinity DataIC50: 890nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed