BDBM50058220 CHEMBL51536::N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-4-methyl-benzamide

SMILES Cc1ccc(cc1)C(=O)NCN1CCN(CC1)c1ccccc1Cl

InChI Key InChIKey=AUCTYGBZIOGIIA-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50058220   

TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058220(N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-4-met...)
Affinity DataEC50:  218nMAssay Description:Agonist activation of human dopamine receptor stimulating mitogenesis in Dopamine receptor D4-transfected CHO pro-5 cells using [3H]thymidine as radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058220(N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-4-met...)
Affinity DataKi:  12nMAssay Description:Binding affinity for human Dopamine receptor D4 expressed in CHO K1 transfected cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058220(N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-4-met...)
Affinity DataKi:  12.0nMAssay Description:Binding affinity of compound towards human dopamine receptor D4 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50058220(N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-4-met...)
Affinity DataKi:  49.0nMAssay Description:Binding affinity towards human dopamine receptor D2 was determined by using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058220(N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-4-met...)
Affinity DataKi:  49nMAssay Description:Binding affinity for human Dopamine receptor D3 expressed in CHO K1 transfected cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058220(N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-4-met...)
Affinity DataKi:  219nMAssay Description:Binding affinity towards human dopamine receptor D4 expressed in CHO cells was determined by using [3H]thymidine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50058220(N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-4-met...)
Affinity DataKi:  466nMAssay Description:Binding affinity for human Dopamine receptor D2 expressed in CHO K1 transfected cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed