BDBM50058199 (S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-naphthalene-1-carbothioyl]-amino}-4-methylsulfanyl-butyric acid::CHEMBL297016

SMILES CSCC[C@H](NC(=S)c1cccc2c(NC[C@@H](N)CS)cccc12)C(O)=O

InChI Key InChIKey=BMXLKSIXSXKJGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058199   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50058199((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of [3H]FPP incorporation into human Ha-Ras by farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50058199((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-nap...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of FTase (unknown origin) assessed as reduction in transfer of [3H]FPP to Ha-RasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed