BDBM50058171 (4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid 2-azepan-1-yl-ethyl ester::CHEMBL50852

SMILES COc1cc(N)c(Cl)cc1NC(=O)OCCN1CCCCCC1

InChI Key InChIKey=RUMRIVRDAKAKKQ-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058171   

Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058171((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataEC50:  100nMAssay Description:concentration which gave a 50% increase in the response to electrical stimulation against 5-hydroxytryptamine 4 receptor in the guinea pig ileum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058171((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataIC50: 207nMAssay Description:The antagonist activity was calculated as the concentration which produced a 50% reduction against 5-hydroxytryptamine 4 receptor in guinea pig ileum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058171((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataKi:  14.5nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed