BDBM50058147 CHEMBL45872::[3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophen-2-yl]-carbamic acid benzo[1,3]dioxol-5-yl ester

SMILES Cc1noc(NS(=O)(=O)c2ccsc2NC(=O)Oc2ccc3OCOc3c2)c1Br

InChI Key InChIKey=IXEOGBXRZGGWAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058147   

TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058147([3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 5.90E+3nMAssay Description:In vitro inhibitory activity against human Endothelin B receptor using radioligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058147([3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 88nMAssay Description:In vitro inhibitory activity against human Endothelin A receptor using radioligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed