BDBM50058144 2-[2-(2,4-Dimethyl-phenyl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL445101

SMILES Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc(C)cc2C)c1Cl

InChI Key InChIKey=CVKQSYMFVKELBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058144   

TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058144(2-[2-(2,4-Dimethyl-phenyl)-acetyl]-thiophene-3-sul...)
Affinity DataIC50: 4.80E+3nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058144(2-[2-(2,4-Dimethyl-phenyl)-acetyl]-thiophene-3-sul...)
Affinity DataIC50: 0.970nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed