BDBM50058138 2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-5-methyl-isoxazol-3-yl)-amide::CHEMBL297783

SMILES Cc1onc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C)c1Cl

InChI Key InChIKey=FUWNXAGLKRZJPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058138   

TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058138(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thio...)
Affinity DataIC50: 3.90E+3nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058138(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thio...)
Affinity DataIC50: 0.630nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed