BDBM50058136 2-[2-(3-Methoxy-phenyl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL297679

SMILES COc1cccc(CC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c1

InChI Key InChIKey=JLOVRXYLWREQNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058136   

TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058136(2-[2-(3-Methoxy-phenyl)-acetyl]-thiophene-3-sulfon...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058136(2-[2-(3-Methoxy-phenyl)-acetyl]-thiophene-3-sulfon...)
Affinity DataIC50: 1.91E+4nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed