BDBM50058132 2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL20168

SMILES Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C)c1C

InChI Key InChIKey=ZKAHRYLIFLDFJH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058132   

TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058132(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thio...)
Affinity DataIC50: 3.30nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058132(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thio...)
Affinity DataIC50: 3.43E+4nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058132(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thio...)
Affinity DataIC50: 3.30nMAssay Description:Inhibitory concentration was determined against selective Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed