BDBM50058127 2-{2-Benzo[1,3]dioxol-5-yl-1-[(Z)-hydroxyimino]-ethyl}-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide; compound with acetic acid ethyl ester::CHEMBL45351

SMILES Cc1noc(NS(=O)(=O)c2ccsc2C(Cc2ccc3OCOc3c2)N=O)c1Cl

InChI Key InChIKey=UHWSBKQVRQYUKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058127   

TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058127(2-{2-Benzo[1,3]dioxol-5-yl-1-[(Z)-hydroxyimino]-et...)
Affinity DataIC50: 4.20E+3nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058127(2-{2-Benzo[1,3]dioxol-5-yl-1-[(Z)-hydroxyimino]-et...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed