BDBM50058085 2-[(3-Methoxy-phenylamino)-methyl]-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide; TFA::CHEMBL416086

SMILES COc1cccc(NCc2sccc2S(=O)(=O)Nc2onc(C)c2Br)c1

InChI Key InChIKey=HSKJJBDJDFTTFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058085   

TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058085(2-[(3-Methoxy-phenylamino)-methyl]-thiophene-3-sul...)
Affinity DataIC50: 933nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058085(2-[(3-Methoxy-phenylamino)-methyl]-thiophene-3-sul...)
Affinity DataIC50: 7.59E+3nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed