BDBM50058073 3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid phenylamide::CHEMBL45269

SMILES Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccccc2)c1Br

InChI Key InChIKey=MEXIZICSHQFANT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50058073   

TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058073(3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thioph...)
Affinity DataIC50: 7.76E+4nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin B receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058073(3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thioph...)
Affinity DataIC50: 166nMAssay Description:In vitro inhibition of endothelin binding to human Endothelin A receptor using [125I]-labeled ET-1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058073(3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thioph...)
Affinity DataIC50: 7.76E+4nMAssay Description:In vitro binding affinity in a radioligand binding experiment by competition with [125I]-labeled endothelin-1 for ETB receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
Immunopharmaceutics

Curated by ChEMBL
LigandPNGBDBM50058073(3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thioph...)
Affinity DataIC50: 166nMAssay Description:In vitro binding affinity in a radioligand binding experiment by competition with [125I]-labeled endothelin-1 for ETA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article