BDBM50058052 CHEMBL3330805::US9260448, 7

SMILES Clc1ccc(cc1)-n1cnc2c(csc2c1=O)-c1ccccc1

InChI Key InChIKey=OHYMOQNKNZPCGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058052   

TargetMetabotropic glutamate receptor 1(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50058052(CHEMBL3330805 | US9260448, 7)
Affinity DataIC50: 66nMAssay Description:Cells of Chem3 Cell Line (HTS145C:Millipore) in which mGluR1 was stably expressed were adjusted to a density of 2×106/ml. 50 μl of the cells wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2016
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 1(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50058052(CHEMBL3330805 | US9260448, 7)
Affinity DataIC50: 162nMAssay Description:Antagonist activity at mGluR1 (unknown origin) expressed in Chem-3 cells assessed as inhibition of glutamate-induced increased intracellular calcium ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed