BDBM50058024 CHEMBL2426247

SMILES Nc1nc2[nH]cc(Cc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)c2c(=O)[nH]1

InChI Key InChIKey=VDHBMZRBPMTLGE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50058024   

TargetDihydrofolate reductase(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50058024(CHEMBL2426247)
Affinity DataIC50: 640nMAssay Description:Inhibition of human DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium parvum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50058024(CHEMBL2426247)
Affinity DataIC50: 49nMAssay Description:Inhibition of DHFR activity of Cryptosporidium hominis bifunctional dihydrofolate reductase-thymidylate synthase assessed as reduction in NADPH oxida...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50058024(CHEMBL2426247)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium parvum)
Yale University

Curated by ChEMBL
LigandPNGBDBM50058024(CHEMBL2426247)
Affinity DataIC50: 380nMAssay Description:Inhibition of thymidylate synthase activity of Cryptosporidium hominis bifunctional dihydrofolate reductase-thymidylate synthase assessed as reductio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed