BDBM50058017 4-[1-(3-Fluoro-propyl)-piperidin-4-ylmethoxy]-benzonitrile::CHEMBL2347003::CHEMBL417001

SMILES FCCCN1CCC(COc2ccc(cc2)C#N)CC1

InChI Key InChIKey=KSMXCGCEJWKWOX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50058017   

LigandPNGBDBM50058017(CHEMBL2347003 | CHEMBL417001 | 4-[1-(3-Fluoro-prop...)
Affinity DataKi:  4.30nMAssay Description:In vitro for binding affinity at sigma-1 receptor by measuring its ability to displace [3H](+)-pentazocine from guinea pig membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50058017(CHEMBL2347003 | CHEMBL417001 | 4-[1-(3-Fluoro-prop...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity to sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50058017(CHEMBL2347003 | CHEMBL417001 | 4-[1-(3-Fluoro-prop...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity to human brain sigma1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Ansto

Curated by ChEMBL
LigandPNGBDBM50058017(CHEMBL2347003 | CHEMBL417001 | 4-[1-(3-Fluoro-prop...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity for Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed