BDBM50057997 4-[2-(3,5-Difluoro-4-methoxy-phenyl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide::CHEMBL43317

SMILES COc1c(F)cc(cc1F)-c1nc(cn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=LCCVBKWYQBQOJT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057997   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057997(4-[2-(3,5-Difluoro-4-methoxy-phenyl)-4-trifluorome...)
Affinity DataIC50: 3.50E+4nMAssay Description:Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057997(4-[2-(3,5-Difluoro-4-methoxy-phenyl)-4-trifluorome...)
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057997(4-[2-(3,5-Difluoro-4-methoxy-phenyl)-4-trifluorome...)
Affinity DataIC50: 30.2nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50057997(4-[2-(3,5-Difluoro-4-methoxy-phenyl)-4-trifluorome...)
Affinity DataIC50: 3.01E+7nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed