BDBM50057992 2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole::CHEMBL296447

SMILES CS(=O)(=O)c1ccc(cc1)-n1cc(nc1-c1ccc2OCOc2c1)C(F)(F)F

InChI Key InChIKey=DLXQYZVXNWRFSG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50057992   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057992(2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 1.10E+3nMAssay Description:Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057992(2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 170nMAssay Description:Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057992(2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057992(2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 280nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057992(2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057992(2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 169nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50057992(2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 1.69E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50057992(2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 1.69E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed