BDBM50057969 4-(2-Phenyl-4-trifluoromethyl-imidazol-1-yl)-benzenesulfonamide::CHEMBL296984

SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nc1-c1ccccc1)C(F)(F)F

InChI Key InChIKey=FQZPECQXBKABHG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057969   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057969(4-(2-Phenyl-4-trifluoromethyl-imidazol-1-yl)-benze...)
Affinity DataIC50: 1.93E+4nMAssay Description:Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057969(4-(2-Phenyl-4-trifluoromethyl-imidazol-1-yl)-benze...)
Affinity DataIC50: 40nMAssay Description:Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057969(4-(2-Phenyl-4-trifluoromethyl-imidazol-1-yl)-benze...)
Affinity DataIC50: 39.8nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50057969(4-(2-Phenyl-4-trifluoromethyl-imidazol-1-yl)-benze...)
Affinity DataIC50: 3.98E+7nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed