BDBM50057805 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-3-[2-hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-5-methyl-1H-pyrimidine-2,4-dione::CHEMBL287942

SMILES Cc1cn(C2CC(C(CO)O2)n2c(=O)c(C)cn(C3CC(N=[N+]=[N-])C(CO)O3)c2=O)c(=O)[nH]c1=O

InChI Key InChIKey=FOSHPJRCRHGLRP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50057805   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institut De Chimie Des Substances Naturelles Cnrs

Curated by ChEMBL
LigandPNGBDBM50057805(1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-...)
Affinity DataEC50:  100nMAssay Description:Reverse transcriptase activity was measured in the culture supernatant, concentration that reduces by 50% the HIV produced in the supernatant.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed