BDBM50057582 4-[5-(7-Methyl-benzo[1,3]dioxol-5-yl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide::CHEMBL29403

SMILES Cc1cc(cc2OCOc12)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=DKYUBWWDQMKPOP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057582   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057582(4-[5-(7-Methyl-benzo[1,3]dioxol-5-yl)-3-trifluorom...)
Affinity DataIC50: 6.74E+5nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057582(4-[5-(7-Methyl-benzo[1,3]dioxol-5-yl)-3-trifluorom...)
Affinity DataIC50: 52nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057582(4-[5-(7-Methyl-benzo[1,3]dioxol-5-yl)-3-trifluorom...)
Affinity DataIC50: 52.5nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed