BDBM50057494 CHEMBL3322814::US9127027, 20::US9127027, LGK-I-119-15::US9422318, LGK-I-119-15

SMILES CCCCCNC(=O)NCCCC\C=C/CCCCCCc1nnn[nH]1

InChI Key InChIKey=UZTSWDCBHOBEFC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50057494   

TargetBifunctional epoxide hydrolase 2(Human)
The Medical College of Wisconsin

US Patent
LigandPNGBDBM50057494(CHEMBL3322814 | US9127027, LGK-I-119-15 | US912702...)
Affinity DataIC50: 11nMAssay Description:Compounds were tested for their ability to inhibit recombinant soluble epoxide hydrolase (sEH) protein. The assay utilizes (3-Phhenyl-oxiranyl)-aceti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Human)
The Medical College of Wisconsin

US Patent
LigandPNGBDBM50057494(CHEMBL3322814 | US9127027, LGK-I-119-15 | US912702...)
Affinity DataIC50: 11nMAssay Description:Compounds were tested for their ability to inhibit recombinant soluble epoxide hydrolase (sEH) protein. The assay utilizes (3-Phhenyl-oxiranyl)-aceti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Human)
The Medical College of Wisconsin

US Patent
LigandPNGBDBM50057494(CHEMBL3322814 | US9127027, LGK-I-119-15 | US912702...)
Affinity DataIC50: 11nMAssay Description:Compounds were tested for their ability to inhibit recombinant soluble epoxide hydrolase (sEH) protein. The assay utilizes (3-Phhenyl-oxiranyl)-aceti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Human)
The Medical College of Wisconsin

US Patent
LigandPNGBDBM50057494(CHEMBL3322814 | US9127027, LGK-I-119-15 | US912702...)
Affinity DataIC50: 11nMAssay Description:Compounds were tested for their ability to inhibit recombinant soluble epoxide hydrolase (sEH) protein. The assay utilizes (3-Phhenyl-oxiranyl)-aceti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetBifunctional epoxide hydrolase 2(Human)
The Medical College of Wisconsin

US Patent
LigandPNGBDBM50057494(CHEMBL3322814 | US9127027, LGK-I-119-15 | US912702...)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human sEH using CMNPC substrate by fluoresecent-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed