BDBM50057424 (R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octan-2-ol

SMILES CN1C2CCC1C(O)(C(C2)c1ccccc1)c1ccccc1

InChI Key InChIKey=XDCPCJCLZKXXMD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057424   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50057424((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibitory activity against Dopamine transporter using 0.5 nM [3H]WIN-35428 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50057424((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibitory activity against Serotonin transporter using 0.2 nM [3H]paroxetine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50057424((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibitory activity against Norepinephrine transporter using 0.5 nM [3H]-radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed