BDBM50057388 Analog of Dynorphin A::CHEMBL2370877

SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H]-1-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](=O)-[#7]-1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#8])=O

InChI Key InChIKey=CNMCWPKZMDXRMO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50057388   

TargetKappa-type opioid receptor(Guinea pig)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50057388(Analog of Dynorphin A | CHEMBL2370877)
Affinity DataKi:  480nMAssay Description:Binding affinity of compound was measured on Opioid receptor kappa 1 by competitive inhibition of radioligand [3H]diprenorphine using cloned receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50057388(Analog of Dynorphin A | CHEMBL2370877)
Affinity DataKi:  910nMAssay Description:Binding affinity of compound was measured on Opioid receptor mu 1 by competitive inhibition of radioligand [3H]DAMGO using cloned receptors transient...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50057388(Analog of Dynorphin A | CHEMBL2370877)
Affinity DataKi:  2.80E+3nMAssay Description:Binding affinity of compound was measured on Opioid receptor delta 1 by competitive inhibition of radioligand [3H]DPDPE using cloned receptors transi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed