BDBM50057366 CHEMBL3322763

SMILES COc1ccc-2c(NC3(CCN(Cc4ccc(cc4)C#N)CC3)c3cccn-23)c1

InChI Key InChIKey=QUVOXAQMOWHLAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057366   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50057366(CHEMBL3322763)
Affinity DataIC50: 562nMAssay Description:Inhibition of human Nav1.7 channel expressed in HEK293 cells assessed as membrane potential after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50057366(CHEMBL3322763)
Affinity DataIC50: 4.58E+3nMAssay Description:Inhibition of human Nav1.5 channel expressed in HEK293 cells assessed as membrane potential after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed