BDBM50057242 4-Hydroxy-3-{(E)-3-[3-(quinolin-2-ylmethoxy)-phenyl]-acryloyl}-benzoic acid::4-hydroxy-3-(3-(3-(quinolin-2-ylmethoxy)phenyl)acryloyl)benzoic acid::CHEMBL276879

SMILES OC(=O)c1ccc(O)c(c1)C(=O)\C=C\c1cccc(OCc2ccc3ccccc3n2)c1

InChI Key InChIKey=WOOGNRDKJXUFCT-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057242   

TargetCysteinyl leukotriene receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50057242(4-Hydroxy-3-{(E)-3-[3-(quinolin-2-ylmethoxy)-pheny...)
Affinity DataIC50: 609nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50057242(4-Hydroxy-3-{(E)-3-[3-(quinolin-2-ylmethoxy)-pheny...)
Affinity DataKd:  609nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed