BDBM50057235 5-Chloro-2-hydroxy-3-{(E)-3-[3-((E)-2-quinolin-2-yl-vinyl)-phenyl]-acryloyl}-benzoic acid::5-chloro-2-hydroxy-3-(3-(3-(2-(quinolin-2-yl)vinyl)phenyl)acryloyl)benzoic acid::CHEMBL11905

SMILES OC(=O)c1cc(Cl)cc(C(=O)\C=C\c2cccc(\C=C\c3ccc4ccccc4n3)c2)c1O

InChI Key InChIKey=QNKLTIIDWGBTQS-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057235   

TargetCysteinyl leukotriene receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50057235(5-Chloro-2-hydroxy-3-{(E)-3-[3-((E)-2-quinolin-2-y...)
Affinity DataIC50: 6.60nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1/2(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50057235(5-Chloro-2-hydroxy-3-{(E)-3-[3-((E)-2-quinolin-2-y...)
Affinity DataKd:  6.60nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed