BDBM50057213 CHEMBL10905::Potassium; (Z)-3-(4-acetylamino-benzyl)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-4-oxo-but-2-enoate

SMILES COc1ccc(cc1)C(=O)C(\Cc1ccc(NC(C)=O)cc1)=C(/C([O-])=O)c1ccc2OCOc2c1

InChI Key InChIKey=OCUILRUINFKWQH-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057213   

TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057213(Potassium; (Z)-3-(4-acetylamino-benzyl)-2-benzo[1,...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of Endothelin A receptor mediated (ET-1) release of arachidonic acid from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057213(Potassium; (Z)-3-(4-acetylamino-benzyl)-2-benzo[1,...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of Endothelin B receptor mediated (ET-3) release of arachidonic acid from human cloned receptors expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed