BDBM50057176 3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-methoxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL276173

SMILES COc1ccc(cc1)C1(OC)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1

InChI Key InChIKey=LSQBMBUQIJTXOS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057176   

TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057176(3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-methoxy-5-(4-me...)
Affinity DataIC50: 300nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057176(3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-methoxy-5-(4-me...)
Affinity DataIC50: 2.50E+4nMAssay Description:Binding affinity against human cloned Endothelin B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057176(3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-methoxy-5-(4-me...)
Affinity DataIC50: 2.50E+4nMAssay Description:Binding affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057176(3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-methoxy-5-(4-me...)
Affinity DataIC50: 300nMAssay Description:Binding affinity for human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article