BDBM50057166 CHEMBL10922::Sodium; (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-3-methyl-phenyl)-4-oxo-3-(3,4,5-trimethoxy-benzyl)-but-2-enoate

SMILES COc1ccc(cc1C)C(=O)C(\Cc1cc(OC)c(OC)c(OC)c1)=C(/C([O-])=O)c1ccc2OCOc2c1

InChI Key InChIKey=RDVXVKVLWVMYGT-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057166   

TargetEndothelin receptor type B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057166(Sodium; (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-3...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Endothelin B receptor mediated (ET-3) release of arachidonic acid from human cloned receptors expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50057166(Sodium; (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-3...)
Affinity DataIC50: 0.980nMAssay Description:Inhibition of Endothelin A receptor mediated (ET-1) release of arachidonic acid from rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed