BDBM50057019 CHEMBL3331613::US9802907, Compound 6

SMILES CCOc1ccc(cc1C#N)-c1nc(C)c([se]1)C(O)=O

InChI Key InChIKey=AIVRMJQFXVTQFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057019   

TargetXanthine dehydrogenase/oxidase(Bovine)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50057019(CHEMBL3331613 | US9802907, Compound 6)
Affinity DataIC50: 25nMAssay Description:Inhibition of bovine xanthine oxidase assessed as inhibition of uric acid formation after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Jiangsu Atom Bioscience and Pharmaceutical

US Patent
LigandPNGBDBM50057019(CHEMBL3331613 | US9802907, Compound 6)
Affinity DataIC50: 2.29nMAssay Description:The inhibition of the activity of xanthine oxidase (XO) is tested through a coupled enzymatic reaction of xanthine oxidase, horseradish peroxidase (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent