BDBM50056767 CHEMBL167577::N-hydroxy-N-[1-(4-isobutylphenyl)ethyl]urea

SMILES CC(C)Cc1ccc(cc1)C(C)N(O)C(N)=O

InChI Key InChIKey=FBLDKAJQWYMCKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056767   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056767(N-hydroxy-N-[1-(4-isobutylphenyl)ethyl]urea | CHEM...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against 5-lipoxygenase catalysis (5-LO) in sonicated rat basophilic leukemia cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056767(N-hydroxy-N-[1-(4-isobutylphenyl)ethyl]urea | CHEM...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase in Human whole blood (HWBL) stimulated with calcium ionophore (A23187) and LTB4 measured by enzyme immunoa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed