BDBM50056448 CHEMBL2371221::N-(1-Carbamoyl-2-phenyl-ethyl)-3-{[(2R,5R)-2-(1H-indol-3-ylmethyl)-2-methyl-3,14-dioxo-1,4diaza-cyclotetradecane-5-carbonyl]-amino}-succinamic acid

SMILES C[C@]1(Cc2c[nH]c3ccccc23)NC(=O)CCCCCCCC[C@@H](NC1=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=HJERLDHULRYYBI-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056448   

TargetGastrin/cholecystokinin type B receptor(Rat)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50056448(N-(1-Carbamoyl-2-phenyl-ethyl)-3-{[(2R,5R)-2-(1H-i...)
Affinity DataEC50:  4nMAssay Description:Effective concentration for the stimulation of Inositol Phosphate accumulation in CHO cells expressing wild-type Cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50056448(N-(1-Carbamoyl-2-phenyl-ethyl)-3-{[(2R,5R)-2-(1H-i...)
Affinity DataKi:  23nMAssay Description:Affinity to inhibit [3H]pCCK-8 specific binding on rat brain Cholecystokinin type B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50056448(N-(1-Carbamoyl-2-phenyl-ethyl)-3-{[(2R,5R)-2-(1H-i...)
Affinity DataKi:  2.47E+3nMAssay Description:Inhibition of [3H]pCCK-8 binding to Guinea pig cortex membrane Cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50056448(N-(1-Carbamoyl-2-phenyl-ethyl)-3-{[(2R,5R)-2-(1H-i...)
Affinity DataKi:  2.47E+3nMAssay Description:Inhibition of [3H]pCCK-8 binding to Cholecystokinin type A receptor of Guinea pig pancreatic membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed