BDBM50056261 (3R,6S)-3-Mercaptomethyl-4-oxo-5-aza-bicyclo[11.3.1]heptadeca-1(16),13(17),14-triene-6-carboxylic acid::CHEMBL147526

SMILES OC(=O)[C@@H]1CCCCCCc2cccc(C[C@@H](CS)C(=O)N1)c2

InChI Key InChIKey=KLCDUNQMSZJEDY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056261   

TargetAngiotensin-converting enzyme(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50056261((3R,6S)-3-Mercaptomethyl-4-oxo-5-aza-bicyclo[11.3....)
Affinity DataIC50: 118nMAssay Description:Inhibitory concentration required to inhibit Angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50056261((3R,6S)-3-Mercaptomethyl-4-oxo-5-aza-bicyclo[11.3....)
Affinity DataIC50: 445nMAssay Description:Inhibitory concentration required to inhibit neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50056261((3R,6S)-3-Mercaptomethyl-4-oxo-5-aza-bicyclo[11.3....)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration required to inhibit thermolysin (TLN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed