BDBM50056245 5-Methyl-6-[(2,3,5,6-tetramethyl-4-pyrrol-1-yl-phenylamino)-methyl]-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL144563

SMILES Cc1c(C)c(c(C)c(C)c1NCc1cnc2nc(N)nc(N)c2c1C)-n1cccc1

InChI Key InChIKey=ODRLNFBWPJLHHF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056245   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056245(5-Methyl-6-[(2,3,5,6-tetramethyl-4-pyrrol-1-yl-phe...)
Affinity DataIC50: 620nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056245(5-Methyl-6-[(2,3,5,6-tetramethyl-4-pyrrol-1-yl-phe...)
Affinity DataIC50: 75nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056245(5-Methyl-6-[(2,3,5,6-tetramethyl-4-pyrrol-1-yl-phe...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed