BDBM50056231 6-[(E)-2-(4-Methoxy-phenyl)-vinyl]-pyrido[2,3-d]pyrimidine-2,4-diamine::6-[2-((E)-4-Methoxy-phenyl)-vinyl]-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL145005

SMILES COc1ccc(\C=C\c2cnc3nc(N)nc(N)c3c2)cc1

InChI Key InChIKey=QVQZNYVDWFENII-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50056231   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056231(6-[2-((E)-4-Methoxy-phenyl)-vinyl]-pyrido[2,3-d]py...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056231(6-[2-((E)-4-Methoxy-phenyl)-vinyl]-pyrido[2,3-d]py...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Toxoplasma gondii (tg)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056231(6-[2-((E)-4-Methoxy-phenyl)-vinyl]-pyrido[2,3-d]py...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056231(6-[2-((E)-4-Methoxy-phenyl)-vinyl]-pyrido[2,3-d]py...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Pneumocystis carinii (pc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056231(6-[2-((E)-4-Methoxy-phenyl)-vinyl]-pyrido[2,3-d]py...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056231(6-[2-((E)-4-Methoxy-phenyl)-vinyl]-pyrido[2,3-d]py...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibitory concentration against Dihydrofolate reductase from Rat liver (rl)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed