BDBM50055953 1-[(3R,5R,10S,13S,17S)-3-Hydroxy-3-(2-hydroxy-phenylethynyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-ethanone::CHEMBL3138017

SMILES [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@](O)(CC[C@]12C)C#Cc1ccccc1O

InChI Key InChIKey=YBAXKRDKUFOWOO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50055953   

LigandPNGBDBM50055953(1-[(3R,5R,10S,13S,17S)-3-Hydroxy-3-(2-hydroxy-phen...)
Affinity DataEC50:  340nMAssay Description:Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055953(1-[(3R,5R,10S,13S,17S)-3-Hydroxy-3-(2-hydroxy-phen...)
Affinity DataIC50: 5.10E+3nMAssay Description:In vitro inhibition of [35S]-TBPS binding to Gamma-aminobutyric acid A receptor in rat brain cortical membranes in the presence of 5 uM GABA (low aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed