BDBM50055900 3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxazol-5-yl]-acetylamino}-propionic acid; TFA::CHEMBL129766::CHEMBL152360

SMILES NC(=N)c1ccc(cc1)C1=NO[C@@H](CC(=O)NCCC(O)=O)C1

InChI Key InChIKey=NENLGQJHPDXGES-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50055900   

TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055900(CHEMBL152360 | CHEMBL129766 | 3-{2-[(R)-3-(4-Carba...)
Affinity DataIC50: 860nMAssay Description:Inhibition of human platelet aggregation induced by ADPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055900(CHEMBL152360 | CHEMBL129766 | 3-{2-[(R)-3-(4-Carba...)
Affinity DataIC50: 140nMAssay Description:Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055900(CHEMBL152360 | CHEMBL129766 | 3-{2-[(R)-3-(4-Carba...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055900(CHEMBL152360 | CHEMBL129766 | 3-{2-[(R)-3-(4-Carba...)
Affinity DataIC50: 240nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50055900(CHEMBL152360 | CHEMBL129766 | 3-{2-[(R)-3-(4-Carba...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of ADP-induced platelet aggregation in human platelet rich plasma (hPRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed