BDBM50055882 4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piperidine::CHEMBL34697

SMILES [O-][N+](=O)c1ccc(CN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)cc1

InChI Key InChIKey=SOXZXITXFAWHRC-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50055882   

TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataIC50: 16.4nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataIC50: 1.77E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataKi:  2.5nMAssay Description:Affinity at rat dopamine transporter using [125I]RTI-55 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [3H]dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataKi:  208nMAssay Description:Inhibition of [3H]norepinephrine uptake at the rat norepinephrine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataKi:  2.15E+3nMAssay Description:Affinity at rat serotonin transporter using [125I]RTI-55 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataKi:  3.58E+3nMAssay Description:Inhibition of [3H]5-HT uptake at the rat serotonin transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed