BDBM50055384 (3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-indol-4-yloxy)-acetic acid::CHEMBL355944

SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1cccc(c1)-c1ccccc1

InChI Key InChIKey=CXAFWBHDYGONMZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50055384   

TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055384((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055384((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055384((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 7nMAssay Description:Compound was tested for inhibition of porcine secretory pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055384((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 570nMAssay Description:Compound was tested for inhibition of human secretory pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055384((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human group IIA phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055384((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human group IB phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055384((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Affinity DataIC50: 7nMAssay Description:Inhibition of pig group IB phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed