BDBM50055287 4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yloxy)-butyric acid::CHEMBL146572

SMILES Cc1c(CC(N)=O)c2c(OCCCC(O)=O)cccc2n1Cc1ccccc1

InChI Key InChIKey=FMBBESBFVOSQSS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50055287   

TargetPhospholipase A2, major isoenzyme(Pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055287(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)
Affinity DataIC50: 3.66E+3nMAssay Description:Compound was tested for the inhibitory activity against human pancreatic PLA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055287(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)
Affinity DataIC50: 610nMAssay Description:Inhibitory activity against porcine pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055287(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibitory activity against human pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055287(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)
Affinity DataIC50: 610nMAssay Description:Compound was tested for the inhibitory activity against porcine pancreatic PLA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055287(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)
Affinity DataIC50: 399nMAssay Description:Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed