BDBM50055112 4-[(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-naphthalene-2-carbonyl)-amino]-benzoic acid::CHEMBL344973

SMILES CC1(C)CC=C(c2cccs2)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O

InChI Key InChIKey=RDUFCVJASUIVOF-UHFFFAOYSA-N

Data  3 IC50  3 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50055112   

TargetRetinoic acid receptor beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50055112(4-[(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-napht...)
Affinity DataKd:  996nMAssay Description:Inhibition of [3H]ATRA binding to baculovirus expressed Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50055112(4-[(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-napht...)
Affinity DataKd:  94nMAssay Description:Inhibition of [3H]ATRA binding to baculovirus expressed Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50055112(4-[(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-napht...)
Affinity DataKd: >10nMAssay Description:Inhibition of [3H]ATRA binding to baculovirus expressed Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50055112(4-[(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-napht...)
Affinity DataEC50:  115nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50055112(4-[(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-napht...)
Affinity DataEC50:  15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRetinoic acid receptor alpha(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50055112(4-[(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-napht...)
Affinity DataIC50: 440nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRetinoic acid receptor beta(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50055112(4-[(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-napht...)
Affinity DataIC50: 3.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRetinoic acid receptor gamma(Human)
Allergan

Curated by ChEMBL
LigandPNGBDBM50055112(4-[(5,5-Dimethyl-8-thiophen-2-yl-5,6-dihydro-napht...)
Affinity DataIC50: 3.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed