BDBM50054982 2-(5-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-ethoxy}-1H-indol-3-yl)-ethylamine::CHEMBL343196

SMILES NCCc1c[nH]c2ccc(OCCOc3ccc4[nH]cc(CCN)c4c3)cc12

InChI Key InChIKey=SFOKJRGOEMIKRG-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054982   

Target5-hydroxytryptamine receptor 1B(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054982(2-(5-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-ethox...)
Affinity DataEC50:  4nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054982(2-(5-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-ethox...)
Affinity DataKi:  1nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054982(2-(5-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-ethox...)
Affinity DataKi:  2.5nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054982(2-(5-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-ethox...)
Affinity DataKi:  14.3nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1A receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed