BDBM50054749 1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-[1,4]diazepane::CHEMBL344990

SMILES Fc1ccc(cc1)C(OCCN1CCCNCC1)c1ccc(F)cc1

InChI Key InChIKey=ALYNPRFOXHAEDW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054749   

TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054749(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-[1,4]d...)
Affinity DataIC50: 143nMAssay Description:Binding affinity against dopamine transporter using radioligand as [3H]GBR 12935More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054749(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-[1,4]d...)
Affinity DataIC50: 17nMAssay Description:Inhibition of dopamine DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054749(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-[1,4]d...)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of [3H]5-HT reuptake at rat serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed