BDBM50054695 CHEMBL3318973

SMILES Clc1ccc(cc1)C1(CC1)c1nnc2c(OC3CCCCC3)cccn12

InChI Key InChIKey=TWPRIJGADLWQSF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054695   

TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50054695(CHEMBL3318973)
Affinity DataEC50:  600nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50054695(CHEMBL3318973)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant 11beta-HSD-1 expressed in HEK293 EBNA cells using [3H]-cortisone and NADPH by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed