BDBM50054603 (Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-[4-(4-trifluoromethyl-phenoxy)-phenyl]-acrylamide::CHEMBL341877

SMILES FC(F)(F)c1ccc(Oc2ccc(NC(=O)C(C#N)C(=O)C3CC3)cc2)cc1

InChI Key InChIKey=LSATVMSOUHYMMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054603   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054603((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-[4-(4-triflu...)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mouse)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054603((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-[4-(4-triflu...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed