BDBM50054565 (2Z,4E)-2-Cyano-3-hydroxy-hexa-2,4-dienoic acid (4-trifluoromethyl-phenyl)-amide::CHEMBL141472::CHEMBL344613

SMILES CC=CC(=O)C(C#N)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=YWNKCKQRBLHMNC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054565   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mouse)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054565(CHEMBL141472 | CHEMBL344613 | (2Z,4E)-2-Cyano-3-hy...)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054565(CHEMBL141472 | CHEMBL344613 | (2Z,4E)-2-Cyano-3-hy...)
Affinity DataIC50: 107nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mouse)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054565(CHEMBL141472 | CHEMBL344613 | (2Z,4E)-2-Cyano-3-hy...)
Affinity DataIC50: 63nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054565(CHEMBL141472 | CHEMBL344613 | (2Z,4E)-2-Cyano-3-hy...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed