BDBM50054511 2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL140323

SMILES COc1ccc(Sc2c(C)[nH]c3nc(N)[nH]c(=O)c23)cc1OC

InChI Key InChIKey=AGHPTCSNQQLEIQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50054511   

TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.40E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.00E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.10E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Pneumocystis cariniMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.10E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.40E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.40E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054511(2-Amino-5-(3,4-dimethoxy-phenylsulfanyl)-6-methyl-...)
Affinity DataIC50: 2.40E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed